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New Impact Factor for Gland Surgery: 1.5

We are pleased to announce that Gland Surgery (GS) has attained its latest impact factor update for the 2023 citation year: 1.5.

Gland Surgery 2023 CiteScore Released: 3.6

We are pleased to announce that the Gland Surgery (GS) has received its 2023 CiteScore: 3.6, ranking 153 out of 551 journals in the Surgery category.

Furthermore, we are delighted to highlight the remarkable achievements made by all AME journals in the CiteScore ranking.

Interviews with Outstanding Authors (2024)

In 2024, many GS authors make outstanding contributions to our journal. Their articles published with us have received very well feedback in the field and stimulate a lot of discussions and new insights among the peers.

Hereby, we would like to highlight some of our outstanding authors who have been making immense efforts in their research fields, with a brief interview of their unique perspective and insightful view as authors.

Reviewer of the Month (2024)

In 2024, GS reviewers continue to make outstanding contributions to the peer review process. They demonstrated professional effort and enthusiasm in their reviews and provided comments that genuinely help the authors to enhance their work.

Hereby, we would like to highlight some of our outstanding reviewers, with a brief interview of their thoughts and insights as a reviewer. Allow us to express our heartfelt gratitude for their tremendous effort and valuable contributions to the scientific process.

2023 Annual Report of GS

Greetings from the Editorial Office of GS!

We are pleased to share the 2023 Annual Report of Gland Surgery.

We would especially like to express our sincere gratitude to the editorial board members, guest editors, reviewers, authors, and readers for all your support and contributions to GS.

We wish you a happy, healthy and prosperous 2024!

Lenvatinib treatment strategy for thyroid carcinoma with malignant pleurisy: a case report

Imaging observations before and after starting lenvatinib. (A) Chest radiography revealed bilateral pleural effusion. (B) Neck computed tomography revealed a tumor in the left lobe. (C) Chest radiography revealed right pleural effusion. (D) Chest radiography revealed the right pneumothorax.

Laboratory parameters-based logistic regression models for rapid screening of thyroid nodules

Comparison of the expression levels of valuable parameters for patients with different types of TNs to healthy individuals. The parameters of (A) high expression level and (B) low expression level in BTN or MTN group compared to the Healthy group. Red lines represent high expression level in BTN or MTN group compared to the Healthy group. Blue lines represent low expression level in BTN or MTN group compared to the Healthy group. The blue line of Glu represent low expression level in MTN group compared to BTN group. The red line of sTSH represent high expression level in MTN group compared to BTN group.

Development and validation of a novel pancreaticojejunostomy strategy based on the anatomical location of the main pancreatic duct that can reduce the risk of postoperative pancreatic fistula after pancreatoduodenectomy

“1² mode” in pancreatoenterostomy mode. 1² mode, single-layer pancreaticojejunostomy with reinforcement of the anterior or posterior wall. (A) If the remaining pancreatic stump could be separated, the pancreatic posterior wall tissue and the serosal layer of the jejunum can be sutured with two horizontal mattress sutures. (B) If the remaining pancreatic stump cannot be separated, the suture is passed through the posterior sides of the pancreatic tissue from behind the pancreatic duct to the posterior wall of the pancreas, and is then sutured to the serosal layer of the jejunum (two horizontal mattress sutures).

Ectopic thyroid follicular carcinoma in the right mandible: a case report

Postoperative pathology revealed a large amount of adenocarcinoma-like tissue with hematoxylin and eosin staining (magnification ×20).

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Vol 13, No 10 (October, 2024)

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Original Article

Laboratory parameters-based logistic regression models for rapid screening of thyroid nodules

Mo Liu, Jing Zhao, Jiayi Zhang, Rui Zhang

PDF Pages: 1673-1683 Full Text (230) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

The differences between unilateral multifocality and bilateral multifocality in papillary thyroid carcinoma: a retrospective cohort study

Zhujuan Wu, Hao Gong, Yuhan Jiang, Tianyuchen Jiang, Anping Su

PDF Pages: 1684-1692 Full Text (195) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Development and validation of a novel pancreaticojejunostomy strategy based on the anatomical location of the main pancreatic duct that can reduce the risk of postoperative pancreatic fistula after pancreatoduodenectomy

Kang Xue, Li Wang, Lang Chen, Xiaofeng Liu, Angzhi Li, Zihe Wang, Shengzhong Hou, Junjie Xiong, Bole Tian

PDF Pages: 1693-1707 Full Text (162) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Early death prediction model for breast cancer with synchronous lung metastases: an analysis of the SEER database

Qiang Li, Tuo Sun, Zhengdong Zhang

PDF Pages: 1708-1728 Full Text (214) Reporting Checklist Peer Review File COI Form Open Access

The impact of gasless insufflation transaxillary endoscopic thyroidectomy on the parathyroid gland injury in patients with thyroid cancer: a retrospective analysis

Yiyan Hong, Hongliang Zhan, Longying Zhang, Kunzhai Huang, Miaomiao Zheng, Fuxing Zhang

PDF Pages: 1729-1739 Full Text (145) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Recurrence and postoperative quality of life after surgical resection of unilateral cT1–T3N1bM0 papillary thyroid carcinoma

Zhilin Qiu, Liang Zhang, Xi Guo, Zhaoming Ding, Jihua Han, Wen Bi, Bing Sun, Jiewu Zhang, Chunlei Nie

PDF Pages: 1740-1751 Full Text (149) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Treatment outcomes in patients with papillary thyroid cancer undergoing radiofrequency ablation of metastatic lymph nodes

Alexandra LaForteza, Emily Persons, Mohammad Hussein, Xinyi Luo, Peter P. Issa, Jessan Jishu, Mohamed Shama, Eman Toraih, Emad Kandil

PDF Pages: 1752-1758 Full Text (297) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Summary of best evidence on prevention of intracranial infection after endoscopic endonasal transsphenoidal pituitary neoplasm resection

Jing Wang, Ping Yu, Qi Chen, Zhijun Han, Qing Wang, Xiaojie Lu, Xuechao Wu, Chun Bian, Mingzhu Gao

PDF Pages: 1759-1769 Full Text (153) Peer Review File COI Form Open Access

Chemotherapy-induced increase in CD47 expression in epithelial ovarian cancer

Ling Zhao, Xueqin Wang, Haining Liu, Jinghe Lang

PDF Pages: 1770-1784 Full Text (183) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Review Article

Diagnostic challenges in calcitonin negative medullary thyroid carcinoma: a systematic review of 101 cases

Mashal Abaalkhail, Jehad Alorainy, Omar Alotaibi, Nawaf Albuhayjan, Abdullah Alnuwaybit, Saleh Alqaryan, Mohammed Alessa

PDF Pages: 1785-1804 Full Text (153) Reporting Checklist Peer Review File COI Form Open Access

Microwave ablation: a technical and clinical comparison to other thermal ablation modalities to treat benign and malignant thyroid nodules

Xinyi Luo, Emad Kandil

PDF Pages: 1805-1813 Full Text (175) Peer Review File COI Form Open Access

Current status of autologous breast reconstruction in Argentina

Claudio Angrigiani, Alberto Rancati, Esteban Spinelli, Karen Barbosa, Julio Dorr, Agustin Rancati

PDF Pages: 1814-1822 Full Text (105) Peer Review File COI Form Open Access

Case Report

Management of cervical bronchogenic cyst via minimally invasive video-assisted thyroidectomy: a report of two cases

Chenyu He, Kewei Jiang, Jianye He, Shan Wang

PDF Pages: 1823-1829 Full Text (150) Reporting Checklist Peer Review File COI Form Open Access

Solitary pituitary metastasis from breast cancer masquerading as a pituitary macroadenoma: a report of 2 rare cases

Lushan Peng, Xianchu Peng

PDF Pages: 1830-1839 Full Text (150) Reporting Checklist Peer Review File COI Form Open Access

Ectopic thyroid follicular carcinoma in the right mandible: a case report

Rong He, Yongzhi Wu, Xue Xiao, Yafei Chen, Xiufa Tang, Yi Men, Bo Han

PDF Pages: 1840-1845 Full Text (153) Reporting Checklist Peer Review File COI Form Open Access

Lenvatinib treatment strategy for thyroid carcinoma with malignant pleurisy: a case report

Shinichi Sakamoto, Mariko Misaki, Keisuke Fujimoto, Taihei Takeuchi, Naoki Miyamoto, Satoshi Fujiwara, Seiya Inoue, Masakazu Goto, Hiroaki Toba, Hiromitsu Takizawa

PDF Pages: 1846-1852 Full Text (141) Reporting Checklist Peer Review File COI Form Open Access

Breast tuberculosis with bone destruction mimicking breast cancer with bone metastasis: a case report and literature review

Li-Xin Li, Ya-Wen Wang, Yuan Lin, Yan-Duo Chen, Xu Chen, Xin Li, Xiao-Lin Zhou, Liang Su, Mei-Ying Lin, Kai Zhang

PDF Pages: 1853-1862 Full Text (188) Reporting Checklist Peer Review File COI Form Open Access

Lumboabdominal migration of injected polyacrylamide hydrogel following breast augmentation: a case report and literature review

Tingting Li, Yu Gui, Xiang Cui, Li Chen

PDF Pages: 1863-1872 Full Text (98) Reporting Checklist Peer Review File COI Form Open Access

Editorial Commentary

Hypoparathyroidism after thyroidectomy: a matter of definition, experience and new adjuncts

Paulina Kuczma, Frédéric Triponez

PDF Pages: 1873-1877 Full Text (72) Peer Review File COI Form Open Access

Optimising the targeted axillary dissection in breast cancer: marker type and timing variability

Adam Ofri, Andrew J. Spillane

PDF Pages: 1878-1882 Full Text (92) Peer Review File COI Form Open Access

Defining high-volume adrenal surgeons to improve patient outcomes

Reagan A. Collins, Colleen M. Kiernan

PDF Pages: 1883-1885 Full Text (57) Peer Review File COI Form Open Access

Original Article

BI-RADS 4 breast lesions: could multi-mode ultrasound be helpful for their diagnosis?

Gang Liu, Meng-Ke Zhang, Yan He, Yuan Liu, Xi-Ru Li, Zhi-Li Wang

Published online: 19 June 2019

PDF Pages: 258-270 Full Text (51929) Open Access

Review Articles

The effect of neck dissection on quality of life in patients with differentiated thyroid cancer

Rossen S. Dimov

Published online: 28 November 2013

PDF Pages: 219-226 Full Text (48875) Open Access

Original Article

The presentation of lymph nodes in Hashimoto’s thyroiditis on ultrasound

Mark R. Jones, Hossam Mohamed, Jennifer Catlin, Daniel April, Zaid Al-Qurayshi, Emad Kandil

Published online: 01 August 2015

PDF Pages: 301-306 Full Text (45257) Open Access

Images of the Issue

Breast magnetic resonance imaging: non-mass-like enhancement

Liuquan Cheng, Xiru Li

Published online: 07 December 2012

PDF Pages: 176-188 Full Text (44960) Open Access

Review Article

The role of noncoding RNA in thyroid cancer

Xinying Li, Zhiming Wang

Published online: 07 December 2012

PDF Pages: 146-150 Full Text (37483) Open Access

Original Article

Preputialplasty: can be considered an alternative to circumcision? When, how, why? Experience of Italian centre

Rossella Angotti, Francesco Molinaro, Francesco Ferrara, Chiara Pellegrino, Edoardo Bindi, Giulia Fusi, Mario Messina

Published online: 03 April 2018

PDF Pages: 228-233 Full Text (36065) Open Access

Review Article

Defining the syndromes of parathyroid failure after total thyroidectomy

Leyre Lorente-Poch, Juan J. Sancho, Jose Luis Muñoz-Nova, Patricia Sánchez-Velázquez, Antonio Sitges-Serra

Published online: 05 February 2015

PDF Pages: 82-90 Full Text (34641) Open Access

Review Article

Recurrence of papillary thyroid cancer after optimized surgery

Clive S. Grant

Published online: 05 February 2015

PDF Pages: 52-62 Full Text (33375) Open Access

Review Article

Speech therapy after thyroidectomy

Wing-Hei Viola Yu, Che-Wei Wu

Published online: 26 October 2017

PDF Pages: 501-509 Full Text (27427) Open Access

Original Article

Is vascular flow a predictor of malignant thyroid nodules? A meta-analysis

Helmi Khadra, Mohamed Bakeer, Adam Hauch, Tian Hu, Emad Kandil

Published online: 28 December 2016

PDF Pages: 576-582 Full Text (26926) Open Access

Images of the Issue

Breast Imaging Reporting and DataSystem (BI-RADS) of magnetics resonance imaging: Breast mass

Liuquan Cheng, Xiru Li

Published online: 10 May 2012

PDF Pages: 62-74 Full Text (25900) Open Access

Images of the Issue

Breast magnetic resonance imaging: kinetic curve assessment

Liuquan Cheng, Xiru Li

Published online: 04 March 2013

PDF Pages: 50-53 Full Text (24502) Open Access

Review Article

Recovery of laryngeal function after intraoperative injury to the recurrent laryngeal nerve

Per Mattsson, Jonas Hydman, Mikael Svensson

Published online: 05 February 2015

PDF Pages: 27-35 Full Text (24075) Open Access

Review Article

Silicone breast implant rupture: a review

Christopher Hillard, Jason D. Fowler, Ruth Barta, Bruce Cunningham

Published online: 19 April 2017

PDF Pages: 163-168 Full Text (22809) Open Access

Review Article

Minimally invasive surgical management of benign breast lesions

Anna Lakoma, Eugene S. Kim

Published online: 16 May 2014

PDF Pages: 142-148 Full Text (22426) Open Access

Original Article

The venous anatomy of the abdominal wall for Deep Inferior Epigastric Artery (DIEP) flaps in breast reconstruction

Warren M Rozen, Mark W Ashton

Published online: 04 September 2012

PDF Pages: 92-110 Full Text (22017) Open Access

Review Article

Breast cancer-related lymphedema: risk factors, precautionary measures, and treatments

Tessa C. Gillespie, Hoda E. Sayegh, Cheryl L. Brunelle, Kayla M. Daniell, Alphonse G. Taghian

Published online: 08 August 2018

PDF Pages: 379-403 Full Text (20777) Open Access

Review Articles

Update on the surgical management of Paget’s disease

Katarzyna Trebska-McGowan, Krista P. Terracina, Kazuaki Takabe

Published online: 30 August 2013

PDF Pages: 137-142 Full Text (20386) Open Access

Systematic Review

Giant juvenile fibroadenoma: a systematic review with diagnostic and treatment recommendations

Michael Sosin, Marisa Pulcrano, Elizabeth D. Feldman, Ketan M. Patel, Maurice Y. Nahabedian, Jason M. Weissler, Eduardo D. Rodriguez

Published online: 01 August 2015

PDF Pages: 312-321 Full Text (20055) Open Access

Review Article

Short and long-term impact of parathyroid autotransplantation on parathyroid function after total thyroidectomy

Gabrielle Hicks, Robert George, Mark Sywak

Published online: 06 December 2017

PDF Pages: S75-S85 Full Text (20039) Open Access

Full Most Read article list >>

Original Article

Trachway video intubating stylet allows for optimization of electromyographic endotracheal tube placement for monitored thyroidectomy

Pi-Ying Chang, Pin-Yang Hu, Yi-Chu Lin, Hsiu-Ya Chen, Feng-Yu Chiang, Che-Wei Wu, Gianlorenzo Dionigi, I-Cheng Lu

Preoperative psychosocial characteristics may predict body image and sexuality two years after risk-reducing mastectomy: a prospective study

Dmytro Unukovych, Hemming Johansson, Yvonne Brandberg

Non-stereotactic method involving combination of ultrasound-guided wire localization and vacuum-assisted breast biopsy for microcalcification

Jeeyeon Lee, Ho Yong Park, Jin Hyang Jung, Wan Wook Kim, Seung Ook Hwang, Taek Ju Kwon, Jin Ho Chung, Youngtae Bae

Histologic evaluation of sentinel and non-sentinel axillary lymph nodes in breast cancer by multilevel sectioning and predictors of non-sentinel metastasis

Piyarat Jeeravongpanich, Tuenjai Chuangsuwanich, Chulaluk Komoltri, Adune Ratanawichitrasin

A high burden of comorbid conditions leads to decreased survival in breast cancer

Ingrid A. Woelfel, Leopoldo J. Fernandez, Michael O. Idowu, Kazuaki Takabe

Evidence based outcomes of the American Society of Breast Surgeons Nipple Sparing Mastectomy Registry

Sunny D. Mitchell, Shawna C. Willey, Peter Beitsch, Sheldon Feldman

The effect of intrathyroidal versus intraperitoneal bevacizumab on thyroid volume and vasculature flow in a rat model

Aaron Smith, Vikrum Thimmappa, John D. Boughter Jr, Christopher Vanison, Courtney B. Shires, Merry Sebelik

BI-RADS 4 breast lesions: could multi-mode ultrasound be helpful for their diagnosis?

Gang Liu, Meng-Ke Zhang, Yan He, Yuan Liu, Xi-Ru Li, Zhi-Li Wang

Shear wave elasticity of breast lesions: would it be correlated with the extracellular matrix components?

Gang Liu, Meng-Ke Zhang, Yan He, Xi-Ru Li, Zhi-Li Wang

Predictive and prognostic value of prognostic nutritional index for locally advanced breast cancer

Yaohui Wang, Bayarmaa Battseren, Wenjin Yin, Yanping Lin, Liheng Zhou, Fan Yang, Yan Wang, Lu Sun, Jinsong Lu

Novel lymphocyte to red blood cell ratio (LRR), neutrophil to red blood cell ratio (NRR), monocyte to red blood cell ratio (MRR) as predictive and prognostic biomarkers for locally advanced breast cancer

Yaohui Wang, Haofeng Wang, Wenjin Yin, Yanping Lin, Liheng Zhou, Xiaonan Sheng, Yaqian Xu, Rui Sha, Jinsong Lu

Review Article

Intraoperative real-time localization of parathyroid gland with near infrared fluorescence imaging

Sung Won Kim, Hyoung Shin Lee, Kang Dae Lee

Speech therapy after thyroidectomy

Wing-Hei Viola Yu, Che-Wei Wu

Preoperative, intraoperative and postoperative anesthetic prospective for thyroid surgery: what’s new

I-Cheng Lu, I-Hua Lin, Che-Wei Wu, Hsiu-Ya Chen, Yi-Chu Lin, Feng-Yu Chiang, Pi-Ying Chang

Are breast cancer stem cells the key to resolving clinical issues in breast cancer therapy?

Hidetaka Shima, Akimitsu Yamada, Takashi Ishikawa, Itaru Endo

BRAF V600E mutation in prognostication of papillary thyroid cancer (PTC) recurrence

Agnieszka Czarniecka, Małgorzata Oczko-Wojciechowska, Marcin Barczyński

Intraoperative neural monitoring in thyroid surgery: lessons learned from animal studies

Che-Wei Wu, Gregory W. Randolph, I-Cheng Lu, Pi-Ying Chang, Yi-Ting Chen, Pao-Chu Hun, Yi-Chu Lin, Gianlorenzo Dionigi, Feng-Yu Chiang

Advances in imaging technologies for planning breast reconstruction

Anita T. Mohan, Michel Saint-Cyr

Current perspectives on radiation therapy in autologous and prosthetic breast reconstruction

Mark W. Clemens, Steven J. Kronowitz

Current opinions on indications and algorithms for acellular dermal matrix use in primary prosthetic breast reconstruction

Michael M. Vu, John Y. S. Kim

Loss of signal in recurrent nerve neuromonitoring: causes and management

Che-Wei Wu, Mei-Hui Wang, Cheng-Chien Chen, Hui-Chun Chen, Hsiu-Ya Chen, Jing-Yi Yu, Pi-Ying Chang, I-Cheng Lu, Yi-Chu Lin, Feng-Yu Chiang

Intraoperative radiotherapy for breast cancer

Norman R. Williams, Katharine H. Pigott, Chris Brew-Graves, Mohammed R. S. Keshtgar

Primary and secondary angiosarcoma of the breast

Tania K. Arora, Krista P. Terracina, John Soong, Michael O. Idowu, Kazuaki Takabe

Overview of indications for nipple sparing mastectomy

Eleni Tousimis, Michelle Haslinger

Autologous reconstruction following nipple sparing mastectomy: a comprehensive review of the current literature

Paul Shay, Jordan Jacobs

Breast cancer-related lymphedema: risk factors, precautionary measures, and treatments

Tessa C. Gillespie, Hoda E. Sayegh, Cheryl L. Brunelle, Kayla M. Daniell, Alphonse G. Taghian

Case Report

Detection of insulinoma using ⁶⁸Gallium-DOTATATE PET/CT: a case report

Samira M. Sadowski, Vladimir Neychev, Candice Cottle-Delisle, Roxanne Merkel, Lily A. Yang, Martha M. Quezado, Richard Chang, Electron Kebebew

A cause of unbearably painful breast, diffuse dermal angiomatosis

Barbara J Adams, Stephanie Goldberg, H. Davis Massey, Kazuaki Takabe

Surgical Technique

Trans-oral glasses-free three-dimensional endoscopic thyroidectomy—preliminary single center experiences

Yi-Ke Zeng, Zhi-Yu Li, Wen-Liang Xuan, Jian-Xing He

Editorial

Contralateral prophylactic mastectomy and quality of life: answering the unanswered questions?

Shoshana M. Rosenberg, Tari A. King

Visualized Surgery

Modified transoral endoscopic thyroid surgery for treatment of thyroid cancer: operative steps and video

Xiao-Wei Peng, Hui Li, Zan Li, Xiao Zhou, Da-Jiang Song, Bo Zhou, Chun-Liu Lv, Wen Peng

Original Articles

Differential protein expressions in breast cancer between drug sensitive tissues and drug resistant tissues

Wenjun Yi, Jing Peng, Yajie Zhang, Fenfen Fu, Qiongyan Zou, Yuanyuan Tang

Review Articles

The prognostic implication and potential role of BRAF mutation in the decision to perform elective neck dissection for thyroid cancer

Jin Woo Lee, Bon Seok Koo

Update on the surgical management of Paget’s disease

Katarzyna Trebska-McGowan, Krista P. Terracina, Kazuaki Takabe

Status quo and development trend of breast biopsy technology

Yan-Jun Zhang, Lichun Wei, Jie Li, Yi-Qiong Zheng, Xi-Ru Li

Perspective

Should we examine sentinel lymph nodes during the operation?

Akimitsu Yamada, Kazuaki Takabe

Research Highlight

Twofer anti-vascular therapy targeting sphingosine-1-phosphate for breast cancer

Kazuaki Takabe, Akimitsu Yamada, Omar M. Rashid, Barbara J. Adams, Wei-Ching Huang, Tomoyoshi Aoyagi, Masayuki Nagahashi

Mini-Review

HuR: a promising therapeutic target for angiogenesis

Rui Dong, Guo-Dong Yang, Nian-An Luo, Ya-Qi Qu

Commentary

Can a seed-sized tool from Texas spare clinically node positive breast cancer patients from a complete axillary dissection?

David M. Fedor, Jeffrey Landercasper

Review Article on Interventional Radiology in Glands

“Super-active surveillance”: MRI ultrasound fusion biopsy and ablation for less invasive management of prostate cancer

Jonathan B. Bloom, Samuel A. Gold, Graham R. Hale, Kareem N. Rayn, Vikram K. Sabarwal, Ivane Bakhutashvili, Vladimir Valera, Baris Turkbey, Peter A. Pinto, Bradford J. Wood

Allo- and auto-percutaneous intra-portal pancreatic islet transplantation (PIPIT) for diabetes cure and prevention: the role of imaging and interventional radiology

Massimo Venturini, Claudio Sallemi, Paolo Marra, Anna Palmisano, Giulia Agostini, Carolina Lanza, Gianpaolo Balzano, Massimo Falconi, Antonio Secchi, Paolo Fiorina, Lorenzo Piemonti, Paola Maffi, Antonio Esposito, Francesco De Cobelli, Alessandro Del Maschio

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Journal Highlight more

Gland Surgery is an international, open access, and peer-reviewed journal indexed by PubMed/PubMed Central and Science Citation Indexed Expanded (SCIE), providing cutting-edge findings and recent scientific advances on diagnosis, prevention, treatment and prognosis of gland diseases, such as breast, thyroid, adrenal, pancreas surgery from a range of fields as biomarkers, imaging, pathology, biology and interventional radiology etc.