Intraoperative ultrasound guided breast surgery: paving the way for personalized surgery

Since the first publication in 1988 about intraoperative ultrasound (IOUS) guided surgery, where Schwartz and colleagues (1) found that ultrasound (US) was an accurate and effective tool for localizing breast masses visualized by US and thus facilitating the surgical excision, multiple manuscripts have reported the use of IOUS to guide BCS in non-palpable breast cancer (2-4).