Time interval of neoadjuvant chemotherapy to surgery in breast cancer: how long is acceptable?

Time interval to treatment is an important question asked by patients every day, but also a question without a definite answer. Clinical practice guidelines do not present specific guidelines on a maximum interval and conflicting results are reported in numerous studies (1-4). This question has also been discussed in various intervals, as of time interval between diagnosis to surgery, and surgery to adjuvant chemotherapy or radiotherapy.