Nipple Sparing Mastectomy: from prophylactic to therapeutic standard

The indications of Nipple Sparing Mastectomy (NSM) are being broadened, including prophylactic or risk-reduction mastectomy and therapeutic mastectomy for both benign and malignant breast diseases (1-3). Concurrently with the development of better screening protocol and preoperative Magnetic resonance imaging (MRI), now the rate of mastectomy is increasing (4).