@article{GS605,
author = {Guohua Yang and Fangqing Xue and Xiaogeng Chen},
title = {Prognostic value of different amounts of cancer stem cells in different molecular subtypes of breast cancer},
journal = {Gland Surgery},
volume = {1},
number = {1},
year = {2012},
keywords = {},
abstract = {Objective: To investigate the differences in the amount of cancer stem cells in different breast cancer
subtypes.
Methods: The specimens of breast cancer tissues were divided into five groups: group A (luminal A type), B
(luminal B type), C (HER-2 + type), D (basal-like type) and E (normal-like type) according to their molecular
subtypes. The cancer stem cell spheres in each group were measured through colony formation method, and
then the relations of the amount of cancer stem cells with the subtypes of breast cancer were analyzed.
Results: The numbers of cancer stem cell spheres in group A and B were (1.1±0.2)/1,000 cells and
(1.3±0.1)/1,000 cells, respectively, and this had no significant difference (P>0.05). The number of cancer
stem cell spheres in group C was (8.6±1.0)/1,000 cells, which was significantly higher than that in group A
and B (both P0.05) but either was significantly
higher than that in the other three groups (all P},
issn = {2227-8575}, url = {https://gs.amegroups.org/article/view/605}
}