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Noninvasive follicular neoplasm with papillary-like nuclear features (NIFTP): a new entity

   
@article{GS34294,
	author = {Elisabetta Macerola and Agnese Proietti and Fulvio Basolo},
	title = {Noninvasive follicular neoplasm with papillary-like nuclear features (NIFTP): a new entity},
	journal = {Gland Surgery},
	volume = {9},
	number = {Suppl 1},
	year = {2020},
	keywords = {},
	abstract = {Since its first official definition in 2016, the new histo-pathological entity of noninvasive follicular neoplasm with papillary-like nuclear features (NIFTP) has attracted much interest among “thyroidologists” worldwide. This is a subset of encapsulated and noninvasive follicular variant papillary thyroid cancer, whose introduction had the intent of de-escalating treatment given its very low malignant potential, approaching to that of follicular adenomas. Many researchers focused on the possibility of preoperatively identifying NIFTP, and investigated their cyto-morphological and molecular characteristics; other ones explored histological and clinical-pathological NIFTP features. Although the majority of published studies confirmed that NIFTP are indolent lesions, some papers did question their low-risk nature. In this brief review, the main aspects of histology, cytology and molecular pathology of NIFTP are discussed based on the current literature.},
	issn = {2227-8575},	url = {https://gs.amegroups.org/article/view/34294}
}