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Identifying the relevant population for neoadjuvant chemo-hormonal therapy combined with radical prostatectomy

   
@article{GS34059,
	author = {Géraldine Pignot and Jochen Walz},
	title = {Identifying the relevant population for neoadjuvant chemo-hormonal therapy combined with radical prostatectomy},
	journal = {Gland Surgery},
	volume = {9},
	number = {2},
	year = {2020},
	keywords = {},
	abstract = {High-risk localized PCa account for about 15% of cases at diagnosis (1) and it is particularly important to establish an appropriate treatment strategy for these patients, considering a multimodal approach and including both local and systemic therapies. Radical prostatectomy (RP) may be an option for selected patients with high-risk localized prostate cancer with an acceptable cancer-specific mortality (10–15%) at 10 years; however, oncological outcomes are decreasing for the subgroups of highest risk patients who have ≥ pT3 disease, Gleason score ≥8, and lymph node invasion. For these patients, the risk of recurrence is up to 70% at 10 years after RP (2).},
	issn = {2227-8575},	url = {https://gs.amegroups.org/article/view/34059}
}