@article{GS2040,
author = {Kecheng Xu and Lizhi Niu and Feng Mu and Yize Hu},
title = {Cryosurgery in combination with brachytherapy of iodine-125 seeds for pancreatic cancer},
journal = {Gland Surgery},
volume = {2},
number = {2},
year = {2013},
keywords = {},
abstract = {A major limit of cryoablation is incomplete destruction of cells in the border zone of the cryogenic lesion in which the tissue temperature is warmer than –20 ℃. The use of iodine-125 seed implantation is likely to be complementary to cryosurgery for treatment of pancreatic cancer. The procedure of cryosurgery and iodine-125 seed implantation is performed with percutaneous approaches under guidance of ultrasound and/or CT. The number of iodine-125 seeds implanted for every patient was 34 in median. Forty-nine patients with locally advanced pancreatic cancer received cryosurgery with combination of iodine-125 seed implantation. During a median follow-up of 18 months, the median of over all survival was 16.2 months. The 6-, 12-, 24- and 36-month overall survival rates were 94.9%, 63.1%, 22.8% and 9.5%, respectively. Compared with patients with cryosurgery alone, combination treatment shows higher the 6- and 12-month survival rates and longer the median survival.},
issn = {2227-8575}, url = {https://gs.amegroups.org/article/view/2040}
}