TY  - JOUR
AU  - Liu, Xiaoli
AU  - Zhou, Ying
AU  - Liang, Nan
AU  - Hong, Yang
AU  - Dionigi, Gianlorenzo
AU  - Sun, Hui
PY  - 2017
TI  - The effect of long-term thyroid-stimulating hormone suppressive  therapy on the gonadal steroid hormones of patients with thyroid  carcinoma after surgery
JF  - Gland Surgery; Vol 6, No 5 (October 26, 2017): Gland Surgery (Prevention & management of complications in thyroid surgery)
Y2  - 2017
KW  - 
N2  - Background: To analyze the effect of long-term thyroid-stimulating hormone (TSH) suppressive therapy on the gonadal hormones and related symptoms in patients after surgery.  Methods: From 2008 to 2011, totally 238 patients were recruited, who underwent thyroid surgery and subsequent TSH suppression treatment in Department of thyroid Surgery, China-Japan Union hospital, Jilin University. Then their postoperative follow-up data (3–8 years) were collected, including operational method, pathological diagnosis, whether processed radioiodine therapy and the period/dose of TSH suppression treatment. In addition, the menstrual cycle, menstruation quantity, whether accompanied with dysmenorrheal and menstrual disorder or not, date of last menstrual period, ages of menopause and so on were also collected.   Results: (I) Neither the level nor the duration of TSH treatment had any function on estradiol (E2) and testosterone (T) in male patients; (II) in the subgroup of patients with TSH treatment for 3–5 years, patients who took high dose of TSH (TSH ≥0.5 U/L) obtained the lower T level compared with the group of medium dose (1.08±0.34 vs. 1.36±0.46 nmol/L, P=0.001); (III) in the medium dose (0.1 IU/L ≤ TSH 
UR  - https://gs.amegroups.org/article/view/16758